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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: ALPL regulates pro-angiogenic capacity of mesenchymal stem cells through ATP-P2X7 axis controlled exosomes secretion

Fig. 7

P2X7 inhibition restores the pro-angiogenic capacity of HPP hBMMSCs. (A) The migration rate of ECs co-cultured with Nor, HPP and HPP + siP2X7 hBMMSCs, as assessed by scratch wound healing assay at 0 and 12 h. (B) The migration ability of ECs, as assessed by migration assay after 6 h of co-culture. (C) The tube formation capacity of ECs, as assessed by tube formation assay after 3 h of co-culture. (D-F) The quantitative assay for scratch wound healing assay (D) migration assay (E) and tube formation assay (F) respectively. All results were generated in three independent experiments. Data were shown as mean ± standard deviation (SD); *P < 0.05; **P < 0.01; ***P < 0.001

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