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Table 3 GO function analysis of differential expressed genes at 48 h exposure of silver-NP-hydrogel

From: Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel

Functional GO pathway

REF.-LIST*/Down- exp#/expected$

P value

nucleobase, nucleoside, nucleotide and nucleic acid metabolic processes

3825/138/81.84

p = 8.40E-12

cell cycle

1840/62/39.37

p = 2.60E-04

mitosis

635/27/13.59

p = 6.90E-04

  1. * reference list, that is all genes number related to the GO pathway;
  2. # down-expressed genes number in this study;
  3. $ expected minimum genes number for activating of signal pathway.
  4. Based on the gene ontology (GO) biological process, the GO pathway, which has theoretically significant activation (p < 1.0E-03), related to down-regulated genes.
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Journal of Nanobiotechnology

ISSN: 1477-3155

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