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Table 2 The release kinetics models of paclitaxel from nanomicelles at pH 7.4 and 5.4

From: Novel water-soluble polyurethane nanomicelles for cancer chemotherapy: physicochemical characterization and cellular activities

Model name

Model

R2

reference

  

pH 7.4

pH 5.4

 

First order

ln (1-F) = - kft

0.974

0.780

[53]

Higuchi model

F  =  K H t

0.990

0.984

[52, 54]

Korsmeyer model

ln F = lnkp + plnt

0.948

0.936

[54]

Hixson-Crowell

1- 1 - F 3  =  K 1/2 t

0.985

0.899

[27]

Weibull

ln[-ln(1-F)] = - βln td + βlnt

0.974

0.780

[52, 54]

Reciprocal powered time

1 F -1= m t b

0.947

0.973

[52]

  1. More details on kinetic models for liberation of drugs from nanoparticles can be found in our previously published paper, see [52].