Figure 4
MRI characterization of bEnd.5 cells incubated with non-targeted and ICAM-1 targeted liposomes. (a) Representative T1 and T2 maps of non-activated and TNFα-activated bEnd.5 cells, incubated for 2 h at 37 °C with 1) no liposomes, 2) L, 3) IgG L and 4) aICAM-1 L. Cellular (b) R1 and (c) R2 measured at 9.4 T. (d) Concentration of gadolinium associated with bEnd.5 cells determined with ICP-MS. * = p < 0.05 vs. all groups, ** = p < 0.05 vs. all non-activated groups, ANOVA with Bonferroni correction. n = 4.