From: Immunoliposome-PCR: a generic ultrasensitive quantitative antigen detection system
Assay format | Range (ng/mL) | LOD(pg/mL)b) | Reference |
---|---|---|---|
Radioimmunoassay | 5 – 320 | 5,000 | |
Chemiluminescence c) | 1 – 25 | 500 | [61] |
Quartz-crystal microbalance | 2.5 – 55 | 500 | [62] |
Microarray fluorescence sensor d) | 0.16 – 9.4 | 400 | [63] |
Time-resolved fluoroimmunoassay e) | 1 – 560 | 280 | [64] |
Electrochemiluminescence f) | 0.21 –2,000 | 200 | [65] |
ICP Mass spectrometry g) | 15 – 250 | 140 | [66] |
Amperometric immunosensor h) | 0.2 – 160 | 60 | [67] |
Microchip electrophoresis i) | 0.06 – 8 | 46 | [68] |
ICP mass spectrometry (immunogold) j) | 0.07 – 1,000 | 30 | [69] |
Colorimetric ELISA | 0.05 – 50 | 20 | |
Single-particle counting k) | 0.017 – 170 | 17 | [72] |
Immuno-PCR | 0.01 – 100 | 10 | [42] |
Electrochemical (quantum dots) l) | 0.01 – 80 | 3.3 | [73] |
Electrochemical (gold nanoparticle) m) | 0.01 – 200 | 1.5 | [74] |
Electrochemical (carbon film) n) | 0.005 – 50 | 1 | |
Surface-enhanced Raman scattering o) | 0.001 – 0.1 | 1 | [77] |
Nanowire sensor array p) | 0.001 – 1 | 0.1 | [78] |
ILPCR | 0.000013 – 13 | 0.013 | this work |