Figure 5
From: Hybrid gold-iron oxide nanoparticles as a multifunctional platform for biomedical application
Cellular interactions of HNPs with A375M cells. A) Cell viability estimated by Trypan blue exclusion assay. Cells incubated with particles (6.25 – 100 μgmL-1) for □ 24, ■72, ■120 and ■168 h (n = 3, ±SE). Values of viability of treated cells were expressed as a percentage of that from corresponding control cells. B) Cellular uptake of in A375M cells. Particles (50 μgmL-1) incubated for 24 h before fixation and silver enhanced staining. Arrows indicate nanoparticles that bound to the cells (on cell membrane or inside the cells). * Denotes significant values compared to control (p < 0.05).