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Table 5 Comparison of the experimental and predicted values of PLGA-CURC prepared under the predicted optimum conditions

From: Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy

Response Predicted value Experimental value Bias (%)a
Y 1 , Particle size (nm) 120.73 129.5 6.77
Y 2 , Polydispersity index 0.13 0.138 6.15
Y 3 , Encapsulation efficiency (%) 92.45 91.4 −1.13
Y 4 , Drug loading (%) 13.56 12.68 −6.49
  1. a Bias was calculated as (predicted value-experimental value)/predicted value X 100.