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Table 5 Comparison of the experimental and predicted values of PLGA-CURC prepared under the predicted optimum conditions

From: Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy

Response

Predicted value

Experimental value

Bias (%)a

Y 1 , Particle size (nm)

120.73

129.5

6.77

Y 2 , Polydispersity index

0.13

0.138

6.15

Y 3 , Encapsulation efficiency (%)

92.45

91.4

−1.13

Y 4 , Drug loading (%)

13.56

12.68

−6.49

  1. a Bias was calculated as (predicted value-experimental value)/predicted value X 100.