Figure 2

Nanoparticle uptake kinetics in 1321N1 and A549 cells. Cells were incubated with NPs of different sizes maintaining the number of particles constant at 6x10¹¹ particles/mL. a. The full cell population behavior is shown for 1321N1 cells incubated with 40 nm NPs without normalization. As the populations displayed a single peak, the population mean was used for comparisons across the different NP sizes. The kinetics of NP uptake for the three NP sizes is shown for 1321N1 (b) and A549 cells (c). Plotted data points correspond to the average of three independent experiments, each with two replicates. Dashed lines correspond to linear fits. Error bars correspond to standard deviations between the three independent experiments.