a) Hybridization of AuNP- oligo probe with genomic DNA. Lane 1: AuNP- oligo probe. Lane 2-3: Hybridization with 22.8 ng and 11.4 ng of restriction digested DNA respectively. Lane 4-5: Hybridization with 22.8 ng and 11.4 ng of sonicated DNA respectively. Lane 6-9: Hybridization with 430 ng, 215 ng, 108 ng, 54 ng of untreated genomic DNA respectively. b) Corresponding results recorded visually after acid challenge.