Figure 3

Intracellular delivery of Qdots using liposomes-only and virus-based liposomes in glioblastoma and HeLa cells. Cell nuclei are denoted by the letter "N" and endocytic pathways are labeled by Transferrin (Tf) (green). Scale bar equals 25 μm in all confocal images. A. Double labeling of glioblastoma (GBM) cells for non-targeted Qdots delivered by using liposomes-only (purple). B. Double labeling of GBM cells for non-targeted Qdots delivered by using virus-based liposomes (VBLs) (purple). C. Measurement of Qdot co-localization with endosomes (black) and cell cytosol (white) when delivered by liposomes-only or VBLs in GBM; D. Double labeling of HeLa cells for non-targeted Qdots delivered by using liposomes-only (purple). E. Double labeling of HeLa cells for non-targeted Qdots delivered by using VBLs (purple). F. Measurement of Qdot co-localization with endosomes (black) and cell cytosol (white) when delivered by using liposomes-only and VBLs.