Figure 1
From: Metastatic prostate cancer cell-specific phage-like particles as a targeted gene-delivery system
Selectivity of the phage clones EPTHSWAT and GDIVTSNS toward target cells PC-3M in comparison with other cells (non-neoplastic prostate epithelial cells, RWPE-1; colon adenocarcinoma cells, HT-2A) and serum. Panel A depicts levels of interaction of phage EPTHSWAT with PC-3M cells, RWPE cells, HT-29 cells and serum; Panel B shows the levels of phage GDIVTSNS interaction with PC-3M cells, RWPE cells, HT-29 cells and serum. Selectivity was estimated as phage recovery (%) = output (cell-associated) phage/input phage. Unrelated phage bearing the guest peptide VPEGAFSS was used as a control.