Figure 7From: Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancerInhibition of cell proliferation (Ki67) in 4T1 breast carcinoma tissue. The mice were treated as described in section 2.3 and tumor slides were immunostained with anti-Ki67. A) Control, B) Magh-citrate, C) Rh2(H2cit)4D) Magh-Rh2(H2cit)4. E) Quantification of Ki67 staining indicated that treatments with Rh2(H2cit)4 and Magh-Rh2(H2cit)4 inhibited tumor cell proliferation by nearly 50% within solid tumor sections when compared to untreated control mice. Data represent mean values ± standard error (n=4/each group) and different letters indicate statistical difference among treatments (p<0.05).Back to article page