Skip to main content

Table 1 Effects of Rh 2 (H 2 cit) 4, Magh-Rh 2 (H 2 cit) 4 and Magh-citrate on hematology and biochemical parameters of female Balb/c mice 23 days after animals’ tumor transplantation 1

From: Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer

Treatment

Control

Rh2(H2cit)4

Magh-Rh2(H2cit)4

Magh-citrate

Hematology parameters

    

WBC (/mm3)

18445.50± 6020.68

24555.00 ± 9693.69

45774.00 ± 11995.51

59060.00 ± 25390.07

RBC (x109/mm3)

8.69±0.27B

10.82± 1.19

10.07 ± 1.03

10.17 ± 0.86

HGB (g/dL)

13.60±0.42

14.75 ± 0.33

14.26 ± 0.14

13.36 ± 0.85

HCT (%)

41.60±1.38

44.62 ± 0.96

44.40 ± 0.39

41.09 ± 2.51

Lymphocytes (%)

28.75±6.65

38.50 ± 13.88

10.80± 3.35

18.71 ± 7.66

Rods (%)

1.25±1.25

0.50 ± 0.50

0.00 ± 0.00

1.43 ± 0.65

Segmented (%)

67.00±7.14

57.67 ± 13.40

84.00 ± 3.36

70.57 ± 7.40

Eosinophils (%)

0.00±0.00

0.00 ± 0.00

0.00 ± 0.00

0.14 ± 0.14

Basophils (%)

0.25±0.25

0.17 ± 0.17

0.00 ± 0.00

0.14 ± 0.14

Monocytes (%)

2.75±0.75

3.17 ± 1.01

5.20 ± 1.11

9.00 ± 4.94

Biochemical parameters

25.20±6.22

25.50 ± 3.57

20.86 ± 2.15

21.33 ± 3.38

ALT (U/L)

0.10±0.00

0.10 ± 0.00

0.10 ± 0.00

0.13 ± 0.02

Creatinine (mg/dL)

125.60±18.59

143.67 ± 14.22

127.57 ± 12.10

112.33 ± 15.23

Serum Fe (mg/dL)

    
  1. Legend: WBC (White Blood Cells); RBC (Red Blood Cells); HGB (Hemoglobin); HCT (Hematocrit); ALT (alanine transaminase).
  2. 1Values are represented as mean ± standard error.
  3. Note: all treatments have no statistical difference when compared with untreated control mice (P>0.05).b.