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Table 1 Effects of Rh 2 (H 2 cit) 4, Magh-Rh 2 (H 2 cit) 4 and Magh-citrate on hematology and biochemical parameters of female Balb/c mice 23 days after animals’ tumor transplantation 1

From: Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer

Treatment Control Rh2(H2cit)4 Magh-Rh2(H2cit)4 Magh-citrate
Hematology parameters     
WBC (/mm3) 18445.50± 6020.68 24555.00 ± 9693.69 45774.00 ± 11995.51 59060.00 ± 25390.07
RBC (x109/mm3) 8.69±0.27B 10.82± 1.19 10.07 ± 1.03 10.17 ± 0.86
HGB (g/dL) 13.60±0.42 14.75 ± 0.33 14.26 ± 0.14 13.36 ± 0.85
HCT (%) 41.60±1.38 44.62 ± 0.96 44.40 ± 0.39 41.09 ± 2.51
Lymphocytes (%) 28.75±6.65 38.50 ± 13.88 10.80± 3.35 18.71 ± 7.66
Rods (%) 1.25±1.25 0.50 ± 0.50 0.00 ± 0.00 1.43 ± 0.65
Segmented (%) 67.00±7.14 57.67 ± 13.40 84.00 ± 3.36 70.57 ± 7.40
Eosinophils (%) 0.00±0.00 0.00 ± 0.00 0.00 ± 0.00 0.14 ± 0.14
Basophils (%) 0.25±0.25 0.17 ± 0.17 0.00 ± 0.00 0.14 ± 0.14
Monocytes (%) 2.75±0.75 3.17 ± 1.01 5.20 ± 1.11 9.00 ± 4.94
Biochemical parameters 25.20±6.22 25.50 ± 3.57 20.86 ± 2.15 21.33 ± 3.38
ALT (U/L) 0.10±0.00 0.10 ± 0.00 0.10 ± 0.00 0.13 ± 0.02
Creatinine (mg/dL) 125.60±18.59 143.67 ± 14.22 127.57 ± 12.10 112.33 ± 15.23
Serum Fe (mg/dL)     
  1. Legend: WBC (White Blood Cells); RBC (Red Blood Cells); HGB (Hemoglobin); HCT (Hematocrit); ALT (alanine transaminase).
  2. 1Values are represented as mean ± standard error.
  3. Note: all treatments have no statistical difference when compared with untreated control mice (P>0.05).b.