From: Mitigating prolonged QT interval in cancer nanodrug development for accelerated clinical translation
Compound tested | Statistically significant inhibition starting at (μM) | Maximal inhibition (%) | Statistically significant reversibility of the Washout | Calculated IC50 (μM) | Voltage dependence |
---|---|---|---|---|---|
HNC-NP | 18 | 24.8 | No | n/a | Yes |
HNC-PS | 6 | 40.2 | No | n/a | Yes |
HNC-PS-C | 6 | 25.2 | No | n/a | Yes |
Curcumin | 12 | 77.8 | No | 8.5 | Yes |
Liposomal curcumin | 6 only | 30 | No | n/a | No |