Figure 4
In vitro cytokine production activity elicited by GLA-AF. (a) MIP-1β production by Mono Mac 6 cells stimulated with unbuffered GLA-AF manufactured with DPPC from different suppliers. (b) MIP-1β production by Mono Mac 6 cells stimulated with unbuffered GLA-AF manufactured by different processes. (c) MIP-1β production by human whole blood stimulated with unbuffered GLA-AF manufactured with DPPC from different suppliers. (d) MIP-1β production by human whole blood stimulated with unbuffered GLA-AF manufactured by different processes. (e) IL-12p40 production by human whole blood stimulated with unbuffered GLA-AF manufactured with DPPC from different suppliers. (f) IL-12p40 production by human whole blood stimulated with unbuffered GLA-AF manufactured by different processes. For all plots, error bars represent standard error of the mean, based on six values (sera from three volunteers assayed in duplicate) and note that one of the GLA-AF batches employed in these studies is not the same one represented in Table 1.