Skip to main content
Figure 3 | Journal of Nanobiotechnology

Figure 3

From: A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7

Figure 3

Adaptive humoral responses induced by synergy adjuvants. Sera were collected from mice after the second immunization and PbCSP antigen-specific IgG1 (Panel A) and IgG2c (Panel B) midpoint titers determined by ELISA. Consistent with the observed cytokine profile the combination induced higher levels of IgG2c, a marker for Th1 immunity in mice. Panel C – the ratio in titers highlights the ability of the combination to induce Th1 biased immunity. * = significantly higher than Antigen alone;† = significantly higher than Liposomes alone; ‡ = significantly higher than IMQ-LS; Single symbol: p < 0.05; Double symbol: p < 0.01. Shown are means with standard error.

Back to article page