Table 2 Comparison of liposome properties
From: A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7
Liposome type | Number of batches | Particle size (Z-ave, nm) | Polydispersity index | GLA retention efficiency (%) | pH before buffer exchange | pH after buffer exchange |
|---|---|---|---|---|---|---|
GLA-LS | 4 | 64 ± 12 | 0.23 ± 0.05 | 81 ± 5 | 2.54 ± 0.06 | 6.73 ± 0.10 |
IMQ-LS* | 4 | 160 ± 25 | 0.21 ± 0.10 | - | 3.48 ± 0.01 | 6.84 ± 0.10 |
GLA/IMQ-LS* | 4 | 141 ± 5 | 0.14 ± 0.02 | 79 ± 10 | 3.53 ± 0.01 | 6.92 ± 0.01 |
LS | 4 | 70 ± 25 | 0.22 ± 0.04 | - | 2.60 ± 0.05 | 6.81 ± 0.07 |