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Table 2 Zeta potential values in different aqueous media of empty and tyrphostin AG-1478 -loaded NLC

From: Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

 

ζ-potential (mV) ± S.D.

Sample

In H2O

In NaCl 0.9 wt%

In PBS pH 7.4

Empty NLC-A

-20.1 ± 5.5

-12.3 ± 4.5

-19.6 ± 3.3

Drug-loaded NLC-A

-30.3 ± 7.7

-13.6 ± 3.7

-20.4 ± 7.7

Empty NLC-B

-18.7 ± 4.6

-10.4 ± 3.6

-15.4 ± 4.2

Drug-loaded NLC-B

-28.5 ± 10.3

-13.2 ± 2.3

-15.1 ± 6.3

Empty NLC-C

-35.7 ± 5.2

-15.9 ± 4.2

-19.7 ± 5.1

Drug-loaded NLC-C

-46.9 ± 8.4

-13.1 ± 2.9

-19.6 ± 5.4

Empty NLC-D

-36.7 ± 5.9

-09.4 ± 2.5

-16.6 ± 3.9

Drug-loaded NLC-D

-38.4 ± 6.5

-11.4 ± 3.5

-16.6 ± 3.7