Development of a novel antimicrobial-releasing glass ionomer cement functionalized with chlorhexidine hexametaphosphate nanoparticles

Table 2 Cumulative fluoride release for specimens with differing levels of nanoparticle substitution at each of 5 time points

	Cumulative fluoride release [ng.mm^-2] (standard deviation in parentheses)
NP substitution [%]	1 h	24 h	8 days	15 days	33 days
0	7.38 (1.69)^a	27.65 (0.85)^a	85.82 (5.68)^a	119.9 (11.0)^a	154.5 (14.3)^{a, b}
1	2.61 (1.11)^b	18.59 (3.12)^{a, b}	70.72 (8.40)^a	106.9 (14.1)^a	148.1 (16.6)^a
2	1.68 (0.73)^b	17.10 (2.33)^b	64.30 (7.68)^a	101.1 (12.2)^a	147.5 (15.7)^a
5	1.74 (0.70)^b	19.31 (4.32)^{a, b}	82.67 (7.49)^a	124.2 (9.2)^a	181.4 (14.0)^{a, b}
10	1.83 (0.96)^b	18.73 (9.50)^{a, b}	81.73 (30.22)^a	122.8 (39.3)^a	184.4 (49.8)^{a, b}
20	2.09 (0.34)^b	23.74 (5.89)^{a, b}	81.73 (13.15)^a	134.6 (19.2)^a	204.4 (23.4)^b

Within each time point, superscript letters indicate statistically homogeneous groups, so figures with different superscript letters are statistically significantly different to a 95% confidence level at that time.

ISSN: 1477-3155