Sensitivity and kinetics of polymer-ligand recognition. (a) Resonant frequency change as a function of BtOMe concentration. Inset is the calibration plot for BtOMe on the MIP (n = 3, 6 injections per surface) and REF (n = 1, 6 injections) films. (b) Variation of observed k
app calculated from the associative part of the frequency vs time response curves for BtOMe binding to MIP and REF films .