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Figure 2 | Journal of Nanobiotechnology

Figure 2

From: Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides

Figure 2

Influence of sonication intensity and vessel volume on the mean size and size distribution of unloaded 72 kDa lauryl ester end-capped PLGA nanospheres. (A) Mean diameter determined by DLS is shown for the nanospheres prepared in either a high or low volume chamber and with either low intensity (38 W) or high intensity (52 W) sonication. Three separate samples were evaluated for each group. (B) Size distribution based on the DLS measurements is shown for a single sample from each of the groups in panel A. Smaller and more uniform nanospheres were obtained using high sonication intensity in a low volume chamber.

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Journal of Nanobiotechnology

ISSN: 1477-3155

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