Figure 2From: Quantum dots improve peptide detection in MALDI MS in a size dependent mannerCrystallised MALDI matrix (Alpha-cyano-4-hydroxycinnamic acid). (A) Tryptic digest of BSA (no purification, no quantum dots). (B) Tryptic digest of BSA (same as in Panel A), containing 50:50% mixes (v/v) of ED-C11-TOL-0560 (566 nm) and ED-C11-TOL-0580 (579 nm) "EviDots". (C) Typical MALDI spectra obtained from tryptic digests of BSA spotted with matrix only or matrix mixed with "EviDots" (D). The amount of protein and the matrix spotted are the same in both cases. Spectra were acquired with 30 laser shots (at 10 Hz) using 50% laser power setting in both cases. In Panel (D) the matrix solution contained a mixture of ED-C11-TOL-0520 (517 nm) and ED-C11-TOL-0540 (544 nm) "EviDots".Back to article page