Real time in vitro studies of doxorubicin release from PHEMA nanoparticles

Table 2 Release exponent and diffusion coefficient of nanoparticles

S.No	HEMA (mM)	EGDMA (mM)	BPO (mM)	pH	n *	Dx10¹⁵* cm² min ^-1
1	12.37	1.06	0.248	7.4	0.46 ± 0.014	1.81 ± 0.054
2	16.49	1.06	0.248	7.4	0.61 ± 0.018	1.98 ± 0.059
3	20.61	1.06	0.248	7.4	0.50 ± 0.015	1.81 ± 0.054
4	24.73	1.06	0.248	7.4	0.55 ± 0.016	1.69 ± 0.051
5	12.37	0.53	0.248	7.4	0.40 ± 0.012	2.16 ± 0.065
6	12.37	1.59	0.248	7.4	0.44 ± 0.013	2.04 ± 0.061
7	12.37	2.12	0.248	7.4	0.45 ± 0.013	2.04 ± 0.061
8	12.37	1.06	0.082	7.4	0.58 ± 0.017	1.81 ± 0.054
9	12.37	1.06	0.165	7.4	0.47 ± 0.014	2.48 ± 0.074
10	12.37	1.06	0.33	7.4	0.58 ± 0.017	1.98 ± 0.059
11	12.37	1.06	0.248	1.8	0.86 ± 0.026	2.61 ± 0.078
12	12.37	1.06	0.248	8.6	0.60 ± 0.018	1.81 ± 0.054

Data showing the release exponent and diffusion coefficient under varying experimental conditions
*Data have been expressed as Mean ± S.D. of at least three determinations.

ISSN: 1477-3155