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Table 1 Antiviral effect of silver nanoparticles against HIV-1 strains

From: Mode of antiviral action of silver nanoparticles against HIV-1

HIV-1 strain Tropism (co-receptor) IC50 (mg/mL)* HeLa cells CC50 (mg/mL)* TI
IIIB T (X4) 0.44 (± 0.3) 3.9 (± 1.6) 8.9
Eli T (X4) 0.42 (± 0.2)   9.3
Beni T (X4) 0.19 (± 0.1)   20.5
96USSN20 T (X4)/M (R5) 0.36 (± 0.2)   12.5
Bal M (R5) 0.27 (± 0.2)   14.4
BCF01 M (R5) 0.37 (± 0.3)   10.5
AZTRV T (X4) 0.19 (± 0.01)   20.5
NNRTIRV T (X4) 0.61 (± 0.24)   6.4
PIRV T (X4) 0.91 (± 0.09)   4.3
3TCRV T (X4) 0.73 (± 0.12)   5.3
SaquinavirRV T (X4) 0.81 (± 0.11)   4.8
  1. *Values represent the mean of the triplicate ± standard error of the mean.
  2. NNRTI: non-nucleoside retrotranscriptase inhibitor, PI: protease inhibitor, RV: resistant virus