Figure 5From: Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIPEffect of DCPIP and DCPIP NPs on VEGF-induced angiogenesis in chicken eggs. CAMs were treated with the reagents indicated in the figure for 48 hours as described in the Materials section (panel A). Visual quantitative results (angiogenesis index) for each experimental variable are also shown (panel B). The blood vessels, in randomly selected CAM fields of the eggs, were photographed and counted. The results from three eggs per treatment are reported as mean ± SD. The asterisk (*) indicates p < 0.05 as compared to empty PLGA NPs.Back to article page