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Figure 5 | Journal of Nanobiotechnology

Figure 5

From: Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers

Figure 5

Verification of the activity of aptamer-conjugated AuNPs. (A) The shift of the SPR maximum clearly indicates the formation of agglomerates in the presence of streptavidin. (B) Schematic illustration of the formation of agglomerates as a function of streptavidin concentration: At low streptavidin concentrations, relatively small agglomerates occur (i). At medium streptavidin concentrations, the tetrameric protein induces the formation of large agglomerates (ii). An excess of streptavidin inhibits the formation of agglomerates by saturation of the aptamers bound to the nanoparticle surface (iii).

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