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Figure 8 | Journal of Nanobiotechnology

Figure 8

From: Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers

Figure 8

Detection of PSMA in human prostate cancer tissue. Detection of PSMA positive structures in prostate cancer tissue sections by immunohistochemical staining using anti-PSMA aptamer (PSMA apt)-conjugated AuNPs. As a negative control, AuNPs conjugated with miniStrep aptamer (miniStrep apt) were used. A polyclonal antibody directed against PSMA (PSMA pAb) was used as a positive control. Positive control was additionally stained with Haematoxylin and Eosin. Black arrows indicate specific staining, while white arrows flag unspecific binding.

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