Figure 12
The PLGA-PEG mediated PS-341 delivery to murine lungs controls Pa -LPS induced CF lung disease. The Cftr-/- mice (n = 3, each group) were treated with Pa-LPS and/or PLGA-PEGPS341. H&E staining verifies the rescue from Pa-LPS induced CF lung disease by PLGA-PEGPS341 in triplicate samples. The PLGA-PEG mediated PS-341 lung delivery controls Pa-LPS induced CF lung disease. Scale: black = 100 μm.