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Table 2 Grouping of animals and time of MRI measurement post-LPS+Gd-DOTA administration

From: Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium

Groups N* MRI time post-LPS+Gd-DOTA administration
TTI   
   Unpurified 2 40 min, 90 min
   purified 12 40 min, 90 min, 3 h, 6 h, 24 h, 48 h
IC-OPC 6 1 h
IC-CPC 5 0 min, 20 min, 30 min, 40 min, 1 h
  1. *One positive control animal receiving transtympanic injection of Gd-DOTA (100 mM) was not counted in the numbers. IC-OPC: intracochlear administration with open perilymph circulation; IC-CPC: intracochlear administration with closed perilymph circulation; TTI: transtympanic injection.