Skip to main content

Table 2 Grouping of animals and time of MRI measurement post-LPS+Gd-DOTA administration

From: Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium

Groups

N*

MRI time post-LPS+Gd-DOTA administration

TTI

  

   Unpurified

2

40 min, 90 min

   purified

12

40 min, 90 min, 3 h, 6 h, 24 h, 48 h

IC-OPC

6

1 h

IC-CPC

5

0 min, 20 min, 30 min, 40 min, 1 h

  1. *One positive control animal receiving transtympanic injection of Gd-DOTA (100 mM) was not counted in the numbers. IC-OPC: intracochlear administration with open perilymph circulation; IC-CPC: intracochlear administration with closed perilymph circulation; TTI: transtympanic injection.
Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us