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Table 1 Spread plate growth of Staphylococcus aureus on solid media in the presence of various Np concentrations.

From: Antimicrobial activity of spherical silver nanoparticles prepared using a biocompatible macromolecular capping agent: evidence for induction of a greatly prolonged bacterial lag phase

 

CFU cm -2

  

[Np ](nM)

Region: 1

2

3

4

x ¯ ±s

 

2903

22

30

35

6

23 ± 13

a

2322

58

67

75

42

61 ± 14

b

1742

118

61

127

82

97 ± 30

b

1161

148

116

126

83

118 ± 27

b

290

325

234

287

380

307 ± 62

c

145

321

327

327

329

326 ± 3

c

29

399

355

479

414

412 ± 51

d

0

314

349

303

361

332 ± 28

c

  1. Averages associated with different letters are significantly different at the p = 0.05 level (ANOVA & multiple range test performed on log-transformed data). The size of the spotted Np areas was approximately 0.255 cm2. The lowest effective concentration provides a Np:CFU ratio of ca. 1011. This calculation is assuming a [Np]-0 CFU intersection occurring at about 2 × 1013 Np s (in 10 μL) and 375 CFU per 0.255 cm2 drop area.