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Table 2 Drop plate growth of Staphylococcus aureus on solid media in the presence of equivalent volumes (20 μL) of various Np concentrations.

From: Antimicrobial activity of spherical silver nanoparticles prepared using a biocompatible macromolecular capping agent: evidence for induction of a greatly prolonged bacterial lag phase

 

CFU mL -1

   

[Np ] (nM)

Exp: 1

2

3

x ¯ ±s

log

Linear

783

0

0

0

0

  

587

0

0

0

0

 

a

392

0

0

0

0

 

a

196

88

25

88

67 ± 36

a

a

157

375

125

288

263 ± 127

b

ab

117

463

413

438

438 ± 25

bc

ab

78

763

450

725

646 ± 171

c

b

39

1638

1050

1813

1500 ± 399

d

c

20

2350

1388

1913

1883 ± 482

d

cd

0

2163

1913

2050

2042 ± 125

d

d

  1. Averages associated with different letters are significantly different at the p = 0.05 level (ANOVA & multiple range test performed on both log- transformed {null values were excluded} and non-log-transformed or linear data). The lowest effective concentration (~ 392 nM) provides a Np:CFU ratio of ca. 1011.