Figure 1From: RNA quantification using gold nanoprobes - application to cancer diagnosticsSchematic representation of Au-nanoprobe assay method. The assay is based on the increased stability of the Au-nanoprobes upon hybridization with the complementary RNA target in solution, while non-hybridized Au-nanoprobes easily aggregate once the solution's ionic strength is increased. Positive: sample in the presence of complementary RNA; Negative: sample in the presence of non-complementary RNA; Blank: Au-nanoprobe alone (no target).Back to article page