Figure 6
From: Optimization of DNA delivery by three classes of hybrid nanoparticle/DNA complexes
Degradation analysis for DNA delivery to 293 cells by six different nanoparticle/DNA complexes over a four week period. Two NP/cationic lipid mixtures (PLGA/DOTAP and PLGA/DC-Chol) and three classes of NP/DNA complexes (out, in and both) were used. Lip (Lip2000/DNA mixture) was a positive control. Top columns show luciferase activity at 3 or 4 day intervals for 4 weeks. Middle graph is (DOTAP) and bottom graph (DC-Chol) NPs. Regression analysis gave straight lines (blue for out, red for in and green for both) for nanoparticles and Lip (purple).