Treatment | Cell line | 24 h | 48 h | 72 h | |||
---|---|---|---|---|---|---|---|
0 (control) | MCF-7 | 100.00 ± 1.50 | A*; a# | 99.94 ± 1.95 | A; a | 100.00 ± 1.06 | A; a |
4T1 | 100.00 ± 1.21 | A; a | 100.00 ± 1.46 | A; a | 100.00 ± 1.34 | A; a | |
MCF-10A | 100.00 ± 3.30 | A; a | 100.00 ± 1.05 | A; a | 100.00 ± 0.92 | A; a | |
Rh 2 (H 2 cit) 4 50 μM | MCF-7 | 94.96 ± 2.44 | A; a | 97.48 ± 2.84 | A; a | 81.19 ± 2.30 | B; a |
4T1 | 90.31 ± 1.38 | A; a | 87.79 ± 2.63 | A.B; a | 81.42 ± 2.56 | B; a | |
MCF-10A | 97.75 ± 3.77 | A; a | 97.82 ± 1.40 | A; a | 84.30 ± 2.55 | B; a | |
Rh 2 (H 2 cit) 4 200 μM | MCF-7 | 89.28 ± 2.60 | A; a | 81.64 ± 2.38 | A; a | 70.13 ± 2.58 | B; a |
4T1 | 79.13 ± 1.44 | A; b | 73.42 ± 2.17 | A.B; a | 68.12 ± 3.64 | B; a | |
MCF-10A | 61.82 ± 6.54 | A; b | 44.19 ± 1.60 | B; b | 30.43 ± 2.69 | C; b | |
Rh 2 (H 2 cit) 4 300 μM | MCF-7 | 85.33 ± 2.14 | A; a | 73.77 ± 2.58 | B; a | 54.14 ± 2.47 | C; a |
4T1 | 73.95 ± 2.54 | A; a | 61.77 ± 1.47 | B; b | 47.79 ± 4.11 | C; a | |
MCF-10A | 39.41 ± 7.47 | A; b | 23.81 ± 0.74 | B; c | 12.78 ± 0.92 | C; b | |
Rh 2 (H 2 cit) 4 500 μM | MCF-7 | 50.08 ± 2.49 | A; a | 25.29 ± 3.46 | B.C; a | 30.39 ± 3.47 | C; a |
4T1 | 46.14 ± 3.49 | A; a | 30.66 ± 1.22 | B; a | 26.07 ± 2.75 | B; a | |
MCF-10A | 25.85 ± 6.46 | A; b | 11.62 ± 1.17 | A.B; b | 5.46 ± 0.46 | C; b | |
Rh 2 (H 2 cit) 4 600 μM | MCF-7 | 28.71 ± 3.90 | A; a | 16.86 ± 1.77 | B; a | 12.16 ± 1.93 | B; a |
4T1 | 29.87 ± 3.67 | A; a | 15.86 ± 0.57 | B; a | 9.97 ± 1.49 | B; a | |
MCF-10A | 13.34 ± 2.43 | A; b | 10.26 ± 1.27 | A; b | 4.76 ± 0.39 | B; b | |
DMSO (0.85%) | MCF-7 | 90.51 ± 5.9 | A; a | 90.93 ± 1.7 | A; a | 96.4 ± 1.4 | A; a |
4T1 | 106.2 ± 1.3 | A; b | 100.6 ± 2.97 | A; a | 43.07 ± 8.2 | B; b | |
MCF-10A | 148.1 ± 6.8 | A; c | 82.45 ± 2.3 | B; a | 63.35 ± 2.2 | C; c | |
Paclitaxel 50 μM | MCF-7 | 70.07 ± 0.4 | A; a | 55.93 ± 1.6 | B; a | 18.92 ± 4.3 | C; a |
4T1 | 68.31 ± 1.2 | A; a | 30.12 ± 0.7 | B; b | 21.51 ± 1.4 | C; a | |
MCF-10A | 80.17 ± 6.7 | A; c | 33.52 ± 1.09 | B; b | 20.95 ± 1.1 | C; a |