Figure 5From: Atomic Force Microscope nanolithography on chromosomes to generate single-cell genetic probesFISH using DOP-PCR products. FISH using DOP-PCR products of the nanodissected microchromosome. Hybridization of the biotinylated probe DNA is detected with FITC-avidin (green signals). Chromosomes are counterstained with DAPI (blue). By DOP-PCR of single nanodissected chicken microchromosome, we have generated a chromosome painting probe.Back to article page