Figure 1
Effect of different adjuvants on relative antibody response to porin YompF. Along the ordinate, percentages with respect to the value for an anti-porin reference serum (serum of mice immunized with pure porin). Along the horizontal axis, the experimental group of animals immunized with: FCA+porin - porin mixed with Freund's complete adjuvant (Sigma); ISCOM+porin - porin incorporated in ISCOMs, prepared as described [11]; TI(PC)+porin - porin incorporated in TI-complex consisting of a cucumarioside A2-2, cholesterol and PC from egg yolk at weight ratio of 3:2:6; TI+porin - porin incorporated in TI-complexes consisting of a cucumarioside A2-2, cholesterol and MGalDG from Ulva fenestrata at weight ratio of 3:2:6. Dose of antigen (denaturated monomeric porin YompF) - 10 μg/mouse.