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Table 3 Scores and assessments of irritation potential of nanoemulsions and surfactant solution tested in the chorioallantoic membrane test

From: Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments

Formulation

Cumulative Score (average)

Assessment

Nanoemulsion1

0

Practically none

Surfactant Solution2

5

Moderate

Positive control3

15

Strong

Negative control4

0

Practically none

  1. 110.00% of rice bran oil, 5.00% of sorbitan oleate, 5.00% of PEG-30 castor oil, 0.05% of BHT antioxidant, 0.50% of preservative and 79.45% of distilled water
  2. 25.00% of sorbitan oleate, 5.00% of PEG-30 castor oil and 90.00% of distilled water
  3. 310% of SLS and 90% of distilled water
  4. 4Saline solution