Figure 2
From: Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration
SWCNTs and PF-127 do not alter membrane capacitance of stBLM. (A) EIS data was analyzed as a Cole-Cole plot of the stBLM before and after exposure to SWCNTs dispersion. The imaginary versus the real (Im(C) vs. Re(C)) parts of capacitance sweeps from 0.1 Hz to 60,000 Hz were plotted as an overlaid color spectrum. Exposure to SWCNTs showed little change to the stBLM indicating no penetration or intercalation into the membrane leaflets. (B) Model fit of the ECM showed little change in α (α > 0.95), suggesting a near perfect membrane. (C and D) Model fit of the normalized CPEstBLM and Rdefect values showed little change in membrane properties after treatment. As a comparison, disruption or perforation of membranes changes Rdefect by more than 100 ×.