Figure 12

A 3-D visualization of the MAS optical system with labels indicating the major components. B. Synthesis reaction chamber with arrows and colors indicating relative reagent velocity within the parallelogram-shaped volume defined by the gasket and across the microarray surface (central rectangle). The reagent flow pattern indicates that the cell geometry prevents stagnant zones which might hinder array uniformity. Relative to the illustration, when mounted in the synthesizer, the reaction chamber is rotated by 45° clockwise, with reagents entering at the bottom and exiting at the top (black spots). The scale of the chamber is defined by the rectangle, which, due to the 1:1 imaging system has the same dimensions as the DMD (14 × 10 mm).