Figure 5
From: In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines
ELISA analysis of anti-drug immune response in BALB/c mice immunized with native (A) or Neo-CAM carrying (B) phages. Sera samples were obtained from mice immunized with the highest phage concentration (1011 phage/dose) following the two boost injections and examined on their ability to bind native (white), Neo-CAM conjugated (black) or Neo conjugated (grey). Neither anti-chloramphenicol nor anti-neomycin antibodies were detected in sera of immunized mice. The average corresponds to 5 mice per group.