Figure 5

Stability of Copper nanoparticles and uptake of citrate protected copper nanoparticles (CuNPs) in Hela cells. (a) TEM image of copper nanoparticles incubated in DMEM medium for 3 hours. (b) Confocal microscopic image of Hela cells treated with 500 μM of Copper nanoparticles for 14 hours. Arrows indicate agglomerated CuNPs. (c) Confocal microscopic image of Hela cells treated with 500 μM of Copper nanoparticles for 14 hours. Arrow indicates agglomerated CuNPs in a membrane bound vesicle (probably perinuclear lysosome). (d) Confocal microscopic image of control Hela cells.