Figure 1

Synthetic scheme for trans-3 isomer [60]fullerene bis-adduct derivative (t3ss). R₁ = CH₂CH₂OCH₂CH₂OCH₂CH₂NHBoc. Reagent and conditions: (i) molar ratio A:B:C 1:2:5, toluene, 2 h at reflux, isolation of trans-3 isomer among the reaction mixture; (ii) CH₃I, CH₂Cl₂, 24 h at 80°C; (iii) HCl (g), CH₃OH, 20 min at 0°C. For more details and procedures see [20].