Relative gene expression of A549 cells treated with Selol-PVM/MA nanocapsules (SPN) at a concentration of 100 μg/mL for 24 h, 48 h and 72 h (a). The following genes were down-regulated: CCNB1, CDC25C and WEE1. The following genes were up-regulated: BCL2, BAX, GPX1 and CYP1A1. *FC > 2.0. Production of reactive oxygen species (ROS) in A549 (b) and HL60 (c) cells treated with SPN at a concentration of 100 μg/mL (SPN). SPN-treated samples were normalized according to the control samples (Ctl). The bars represent the means ± standard error. *p < 0.001.