Development of antibody functionalized magnetic nanoparticles for the immunoassay of carcinoembryonic antigen: a feasibility study for clinical use

Table 2 CEA concentrations, ϕ_CEA, spiked in serum, for the detections of IMR signals

ϕ_CEA(ng/ml)	Mean IMR value(%)	Standard deviation of IMR(%)	Converted CEA concentration ϕ_CEA-IMR(ng/ml)
0.10	1.07	0.014	0.08 ± 0.07
0.20	1.10	0.014	0.24 ± 0.08
3.85	1.51	0.021	3.38 ± 0.21
5.00	1.70	0.021	5.58 ± 0.28
10.0	1.97	0.021	9.99 ± 0.43
50.0	2.71	0.028	49.49 ± 3.83
100	2.93	0.035	101.7 ± 15.0
500	3.14	0.028	482.6 ± 184.7
1000	3.19	0.028	1269.6 ± 560

The mean values and the standard deviations of the detected IMR signals are shown. Using the detected IMR signals, the CEA concentrations, ϕ_CEA-IMR, derived using Eq. (1), are listed in the right-most column.

ISSN: 1477-3155