Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers

Table 1 Mean size (nm), polydispersity index (PDI) and ζ-potential (mV) in bi-distilled water, phosphate buffer solution (PBS) and NaCl 0.9 wt% of empty and Fluticasone propionate (FP)-loaded nanoparticles

Sample	Dispersing medium	Mean size (nm)	PDI	Zeta potential (mV)(± S.D.)	*EE%*(w/w)
Empty	PBS pH 7.4	133.7	0.243	−15.1 ± 3.78	-----
	NaCl 0.9%	132.5	0.215	−12.3 ± 4.16	-----
	H₂O	115.9	0.285	−27.8 ± 3.21	-----
FP-loaded	PBS pH 7.4	178.7	0.266	−14.3 ± 2.44	76.8 ± 0.04
	NaCl 0.9%	189.6	0.244	−13.3 ± 4.56	76.8 ± 0.05
	H₂O	129.9	0.330	−31.3 ± 4.50	76.8 ± 0.04
Empty 4 months)	H₂O	137.9	0.247	−26.6 ± 3.13	-----
Empty (10 months)	H₂O	149.9	0.235	−25.4 ± 2.15	-----
FP-loaded (4 months)	H₂O	143.2	0.323	−28.3 ± 2.72	74.7 ± 0.06
FP-loaded (10 months)	H₂O	145.6	0.334	−27.5 ± 4.50	72.5 ± 0.03

ISSN: 1477-3155