Figure 4
From: Toxicity of silver nanoparticle in rat ear and BALB/c 3T3 cell line
The threshold shifts in the rats caused by the transtympanic injection of the AgNPs are shown by auditory brainstem response (ABR) measurements. 40 μl of either AgNPs at different concentrations or water were delivered into the middle ear via transtympanic injection. The ABR were measured before and after injection at defined time points. The threshold shift = the threshold post injection-threshold pre-injection. cl: click. **p < 0.01 (independent sample t-test).