Figure 10

KEGG pathways enriched as indicated by the FeRGs. A and B: KEGG pathways enriched by the induced genes in the THP-1 cells. C and D: KEGG pathways enriched by the induced genes in the HepG2 cells. E and F: KEGG pathways enriched by the repressed genes in the THP-1 cells. G and H: KEGG pathways enriched by the repressed genes in the HepG2 cells. The pathways with p values less than 0.05 are shown as bars in deep colors. The pathways with p values over 0.05 are shown as bars in light colors. In each plot, the pathways were aligned from left to right according to their p values from low to high. Abbreviations in the pathway names: M, metabolism; B, biosynthesis. The pathway that was significantly activated by both doses of FeNPs is highlighted by shading.