Figure 7
Top 10 GO terms enriched by induced and repressed genes in the two cell lines. A and B: GO terms enriched by the induced genes in the THP-1 cells. C and D: GO terms enriched by the induced genes in the HepG2 cells. E and F: GO terms enriched by the repressed genes in the THP-1 cells. G and H: GO terms enriched by the repressed genes in the HepG2 cells. *Negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. PolII, polymerase II. The p values for all GO terms are less than 0.05. In each plot, the GO terms were aligned from left to right according to their p values from low to high. 50-up, 100-up, 50-down, and 100-down, see Figure 3. Inset: Venn analysis of all GO terms enriched by the induced genes (a) and repressed genes (b) in the THP-1 and HepG2 cell lines. T-50, H-50, T-100, and H-100, see Figure 4. The numbers in overlapped areas represent the overlapping GO terms.