Figure 6
MR imaging of hVM-MNP labeled cells in rat brain. Cell suspensions (3x105 cells) were transplanted into the left (hVM cells) and right (hVM-MNP-Cy3 labeled cells) intact striata. MRI was performed 48 h (A), 2 weeks (B), 4 weeks (C) and 8 weeks (D) after cell transplantation. MNPs can be easily detected by MRI as dark hypointense signals in the area where the MNPs-labeled cells have been injected. No MRI signal was detected when unlabeled hVM cells were transplanted (left striatum). The arrow in C shows a small percentage of hVM cells following the injection tract. Scale bar: 2 mm.