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Figure 2 | Journal of Nanobiotechnology

Figure 2

From: Superparamagnetic core/shell GoldMag nanoparticles: size-, concentration- and time-dependent cellular nanotoxicity on human umbilical vein endothelial cells and the suitable conditions for magnetic resonance imaging

Figure 2

GMNP uptake. Prussian blue staining of HUVECs ( A-U, x200). Cells were incubated with 5, 10, 25, 50 and 100 μg/mL 30 nm GMNPs for 12 hours ( B-F ), 5, 10, 25, 50 and 100 μg/mL 50 nm GMNPs for 12 hours ( G-K ), 25 μg/mL 30 nm GMNPs for 3, 6, 12, 24 and 48 hours ( L - P ), and 25 μg/mL 50 nm GMNPs for 3, 6, 12, 24 and 48 hours ( Q - U ). Control cells are shown in (A). The labeling rates of 30 and 50 nm GMNPs at different concentrations and for durations are shown in ( V - W ). TEM of control HUVECs (X), HUVECs labeled with 25 μg/mL 30 nm GMNPs ( Y, black arrow) and 50 nm GMNPs ( Z, black arrow) for 12 hours.

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